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Pharmachologic effect
Pharmacological action - somatotropic.
Interacts with specific membrane receptors, increases the intracellular content of cAMP, activates protein kinases and protein synthesis. Strengthens bone metabolism and accelerates linear skeletal growth, maintains normal body structure, stimulates muscle growth, muscle strength, cardiac output, and promotes fat mobilization. Increases the serum concentration of insulin, insulin-like growth factor (IRF-1) and its binding protein (IRFSB-3). The number of receptors that bind LDL in the liver increases, and the profile of lipids and lipoproteins in serum changes. It inhibits the release of sodium, potassium and phosphorus, increases physical endurance, regulates the balance of neurotransmitters in the brain, improves memory and increases vitality.
Pharmacodynamics
Stimulates growth and increases body weight.
Somatropin synthesized by molecular cloning is fully contained in the preparation genatropin, being an intensive regulator of the metabolic process.It has a huge effect on the metabolism of organic fat-like substances, proteins, simple and complex sugars in the body. This hormone supports the entire constitution of the body, its focused purpose is to induce all available muscles to grow and normalize the metabolic process. In particular, subcutaneous adipose tissue accumulating around the abdominal organs is sensitive to somatotropin. The synthesized hormone increases the serum concentration of the single-chain proteins IGF1 and IGF2, thereby improving overall health and slowing down the human aging process. In addition, the use of the drug has an enhanced interaction on water-salt metabolism, stimulating liver recipients to the formation of low-density lipoproteins, which helps to avoid such pathologies as:
Due to its unique pharmaceutical effects on the human body, growth hormone has only positive reviews, providing the following effects: