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Pharmacodynamics
Somatropin has a pronounced effect on the metabolism of fats, proteins and carbohydrates. In children with growth hormone (GH) deficiency, somatropin stimulates the growth of skeletal bones in length, acting on the epiphysis plates of the tubular bones. In both adults and children, somatropin helps to normalize body structure by increasing muscle mass and reducing body fat mass. Visceral adipose tissue is especially sensitive to the action of somatropin. In addition to enhancing lipolysis, somatropin reduces the supply of triglycerides to body fat. Under the influence of somatropin, the concentration of insulin-like growth factor I (IGF-I) and its binding protein (IGF-SB3, insulin-like growth factor binding protein) increases.
In addition, the following effects have been demonstrated
Exchange of fats. Somatropin activates LDL receptors in the liver and changes the profile of lipids and lipoproteins in the blood. In general, the appointment of somatropin to patients with GH deficiency leads to a decrease in LDL and apolipoprotein B in the blood. A decrease in cholesterol concentration is also observed.
Metabolism of carbohydrates. Somatropin increases insulin release, but fasting glucose concentration usually does not change. Children with hypopituitarism may develop fasting hypoglycemia. This condition is reversible with the introduction of somatropin.
Water and mineral exchange. GH deficiency is associated with a decrease in plasma and extracellular fluid volume. The appointment of somatropin leads to a rapid increase in both parameters. Somatropin promotes the retention of sodium, potassium and phosphorus.
Bone metabolism. Somatropin stimulates bone metabolism. Long-term treatment with somatropin in children with GH deficiency and osteoporosis leads to the normalization of the mineral composition and bone density.
Physical activity. Long-term somatropin replacement therapy leads to an increase in muscle strength and physical endurance. Cardiac output is also increased, although the mechanism of this action is not fully understood. The decrease in peripheral vascular resistance may partially explain this effect of somatropin.
Omnitrope for fitness and bodybuilding
Growth hormone Omnitrope is used in official medicine and in sports pharmacology. It is in demand among athletes whose training is based on extreme physical activity. Main applications: fitness, bodybuilding, bodybuilding, powerlifting. Omnitrope injections help in solving such problems:
Omnitrope and sports applications
The drug is in the form of a ready-made transparent solution for subcutaneous injection. The substance is placed in a cartridge made of transparent colorless borosilicate glass. The cartridge is intended for use in syringe pens. The pen itself is not included in the kit.
To support sports training Omnitrope.
Omnitrope is used in a specific manner and in specific dosages. The dosage of the drug is selected individually, taking into account the physical data of a particular athlete.
The main requirements for obtaining the desired effect from taking the drug Omnitrope:
Dosages of the drug Omnitrope. Omnitrope in sports
The drug should be taken with caution and only if there are contraindications. Before taking the drug, you need to consult with your doctor to exclude the presence of contraindications. Initially, Omnitrope is taken in reduced dosages to test the body's response to therapy.
Approximate dosages of the drug Omnitrope